Top 7 Safety Data Sheet Software of 2026

Why use Mitti (by SafetyCulture)?

This top-rated digital solutions provider offers one of the most effective safety data sheet (SDS) software, helping companies to digitize, organize, and disseminate information about chemical compounds, their hazards, and precautions to take when working with them. With its wide array of features, Mitti (by SafetyCulture) safeguards the health and safety of workers in high-risk settings and ensures the company’s compliance with OSHA and Lab Safety standards.

Features:

• Create electronic safety data sheets and organize the data collected in a central database, easily retrievable when required.

• Use relevant checklists while doing routine inspections and audits in compliance with mandated regulations.

• Raise issues and immediately assign preventive or corrective actions.

• Generate reports about chemical hazards and the steps taken to mitigate or correct the problem and add media attachments to provide the full context of the incident.

• Provide instruction or training to employees so they can understand and interpret SDS information.

Why use SDS Manager?

SDS Manager is a cloud-based SDS management platform built for businesses of all sizes, from SMBs to large enterprises. They help organizations comply with global safety standards such as OSHA, GHS, REACH, etc., while ensuring employees have instant access to the latest chemical information. They also offer AI-powered tools and QR code features to access safety data in seconds to enhance workplace safety.

Features:

• Centralized SDS management and search

• Automatic SDS updates

• One-click GHS and transport label generation

Why use SpheraCloud?

SpheraCloud’s chemical data management solutions help companies ensure safety in the workplace and compliance with regulations through easy-to-use and update safety data sheets and optimize operations through automated processes.

Features:

• Easy-access data

• Automated reporting

• End-to-end visibility

Why use BackPack?

This digital platform provides comprehensive solutions for managing chemicals efficiently, from use and storage to transport for disposal. They have a large chemical database that undergoes continuous updates to ensure companies using their system are at par with standards and abide by regulations.

Features:

• SDS management

• Registers and manifest

• Reporting with documentation

Why use VelocityEHS?

This chemical and SDS software helps companies manage hazardous chemicals, from organizing them in a database, properly labeling them on-site, tracking their location, and comprehensive reporting. They also provide a HazCom e-book available to employees so they know how to handle these substances.

Features:

• Inventory tracking with auto-updates

• SDS offline access

• Regulatory reporting

Why use Labelmaster?

An industry-leading digital solution for hazard communication, this helps companies safely operate in high-risk sites and conditions and ensure compliance with changing regulations. Aside from their comprehensive software features, they also offer safety products (e.g., storage containers, labels, placards, etc.), employee training, and site inspections.

Features:

• Identification and classification

• Regulatory monitoring

• Compliance assessments

Why use 3E Protect?

This SDS and chemical management software is an award-winning digital solution that improves the health and safety situation of the workforce by decreasing potential risks in the workplace. Their extensive SDS database is available in various languages and may be accessed any time, anywhere.

Features:

• Document storage

• Inventory management

• Chemical labeling